F 77, asymptomatic dermal papules, both thighs
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Perivascular and interstitial lymphohistiocytic infiltration.
Mononuclear cells in between the collagen bundles separated by mucinous material stained blue by Colloidal iron stain.
Histiocytes and multinucleated giant cells around ill-defined hypocellular collagenous tissue.
Granuloma annulare (GA) is a benign inflammatory dermatosis of
Granuloma annulare is relatively common disease that occurs in all
ages, but it is rare in children. F > M.
Clinically GA presents as dermal papules and annular plaques.
It may be localized (most common), generalized or subcutaneous.
Most cases of GA resolve spontaneously.
GA may be associated with Type 1 diabetes mellitus and
hematopoietic malignancies (lymphoma and leukemia).